This study critically examines the political economy of genetically modified organism (GMO) foods in Africa, arguing that their proliferation reflects a neocolonialist strategy aimed at economic and ideological recolonization. While proponents of GMO technology flaunt its potential to enhance crop resilience and alleviate hunger, this research interrogates the geopolitical and economic interests embedded in its promotion, particularly by Western governments, multinational agribusinesses, and philanthropic actors such as the Bill & Melinda Gates Foundation. Drawing on postcolonial theory and dependency paradigms, the paper explores how GMO adoption in Africa is shaped not by local agency but by external pressure, conditional aid, and intellectual property regimes that favor foreign corporations. The analysis highlights how seed patenting, restrictive trade agreements, and donor-driven policy frameworks erode indigenous farming systems and entrench a cycle of technological reliance. Through case studies in Nigeria, Kenya, and South Africa, the research reveals how GMO policies often bypass democratic consultation and marginalize smallholder farmers, reinforcing asymmetrical power relations reminiscent of colonial governance. The paper thus argues that the GMO agenda in Africa is not merely a scientific or humanitarian endeavor but a strategic extension of global capital interests, cloaked in the rhetoric of development. Ultimately, the study calls for a reimagining of food sovereignty in Africa – one that centers indigenous knowledge and genuine self-determination in agricultural policy.
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